Publications

Multiscale, mechanistic model of Rheumatoid Arthritis to enable decision making in late stage drug development

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An integrated quantitative systems pharmacology virtual population approach for calibration with oncology efficacy endpoints

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Quantitative systems pharmacology model of erythropoiesis to simulate therapies targeting anemia due to chronic kidney disease

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Can a propensity score matching method be applied to assessing efficacy from single-arm proof-of-concept trials in oncology?

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Tumor dynamics in patients with solid tumors treated with pembrolizumab beyond disease progression

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Beyond the single average tumor: Understanding IO combinations using a clinical QSP model that incorporates heterogeneity in patient response.

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Estimating Smoking Cessation Rates and Smoking Prevalences Using Public Data and a Published Dynamic Model.

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Lesion-level heterogeneity of radiologic progression in patients treated with pembrolizumab.

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Incorporating lesion-to-lesion heterogeneity into early oncology decision making.

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Hallmarks of neurodegenerative disease: A systems pharmacology perspective.

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