Clinical Pharmacology is a discipline that aspires to maximize the therapeutic’s efficacy without leading to adverse events and in certain scenarios aids in identification of the appropriate patient population where the therapeutic will have maximal effect. Clinical pharmacologists work towards enhancing patient care by identifying the optimal use of a certain therapeutic, while developing a more comprehensive understanding of the intended efficacy and adverse events both short term and long term.
At Vantage, our M&S approach towards Clin Pharm have focused on the following aspects
- Establish Proof of Mechanism
- Connecting the mechanistic model to the clinical PD outcomes
- Identify optimal Recommended Phase 2 Dose (RP2D)
Vantage RA Model integrates mechanistic pathways & disease scores to aid Clinical Trial designRead More