Drug Discovery
As researchers to identify the right target and select molecules with suitable characteristics modulate it, M&S supports both proof of mechanism analyses (proximal PK & PD effects) while also providing an early sense for ‘proof of concept’ downstream effects in the clinic.
At Vantage, our focus in drug discovery has been on
- Connect Target-Pathway-Disease
- Identify optimal molecule characteristics and support lead selection
Key Questions that M&S can address
- Based on target binding data, can we decide which molecule has the optimal characteristics to become a lead candidate?
- Can we predict downstream effects of modulating this target and estimate the effect on ultimate PD biomarkers measured in the clinic?
