Quantitative Systems Pharmacology guided MABEL estimation for T-cell Engagers (TCE): A case study to support model-informed first-in-human dose selection
Optimal therapeutic combinations for Phase 3 UC trial design- recommendations from a QSP platform model
Model-informed dose priming strategy for T cell engagers: Leveraging early clinical data to mitigate CRS
Bridging Preclinical Data and Human Dose Selection for ADCs: Lessons from Approved Molecules
Quantitative Systems Pharmacology (QSP) Modeling of efficacy and nausea of GLP-1 mono and dual (GLP-1/GIP) receptor agonists (RA) to support weight management and glycemic control in obese patients
Evaluating antibody drug conjugate (ADC) combinations using the platform Quantitative Systems Pharmacology (QSP) model
A Unified Mechanistic Framework for Modeling Short- and Long-Acting siRNAs: Impact of RISC Stability on PD Durability
Model-Informed Strategies for GLP-1 RA Development: Linking PKPD to Weight Loss and Glycemic Control
Predicting Phase3 efficacy of combination therapy in Ulcerative Colitis #IBD
From Xenograft to Clinic: QSP-guided dosing and step-up strategy for CD3×HLA-G T Cell Engagers TCE
